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Resveratrol, 300 MG
Capsules
Research shows that only
2-3 % of the antioxidants you eat can even get to your skin, the next
question is – is that enough to protect you from free radical damage? That’s
merely a trickle of the antioxidant protection you need if you are serious
about putting the brakes on aging. Perhaps, the best anti-aging strategy for
you would be to take a powerful antioxidant that can deliver the supreme free
radical protection that your body demands – RESVERATROL! Resveratrol deeply
penetrates the center of your cell’s nucleus, giving your DNA time to repair
free radical damage. It also supports cell functions in the heart and brain
so that you can:
• Prevent the
rampant spread of cancer cells at any stage; Keep your blood circulation
going smoothly and prevent arterial damage; Protect your brain from the
tragic development of Alzheimer’s
• Prevent
neurological disorders such as strokes, ischemia, and Huntington’s
disease
But there’s more -
Resveratrol lives up to its title “Miracle Antioxidant” in more ways than you
can ever imagine! Scientific reports show that Resveratrol activates your
body’s natural “longevity gene,” helping you to:
• Maintain healthy
metabolism and burn fat faster, Have healthier, firmer skin and muscle tone
• Slow down aging
down to the cellular level!
A natural
defense mechanism found in plants, Resveratrol has a number of health
benefits; when taken as a supplement, including the lowering of blood sugar levels
and improvements in the immune system. Several scientific studies have
concluded that Resveratrol and other antioxidants found in plants – known as
polyphenols – can help prevent and treat certain types of cancer.
Antioxidants help protect cells from being damaged by free radicals and
potentially becoming cancerous.
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Where CoQ10 is good, ubiquinol
is actually 10 times stronger and better. One of the unique elements in
the aging process is free radical production. These free radicals are oxygen
atoms which are deficient in electrons that become highly reactive and can
cause potential damage to your tissues and DNA. Your body requires this
reduced form of Co Q10 to help you limit free radical production, thereby
dramatically affecting the aging process.
Our body naturally
produces CoQ10 which converts fats and sugars into cellular energy. However,
our body's production of CoQ10 declines as we age. Changing your daily
supplement of CoQ10 to the more absorbable form of Ubiquinol is particularly
beneficial if you are aged over 40, suffer from diabetes or liver disease,
experience tiredness and low energy, take statin drugs or currently take
large doses of CoQ10, above 150mg per day. Fewer milligrams of ubiquinol are
required to achieve better benefits than conventional CoQ10 and although 10
times stronger, ubiquinol is not 10 times more expensive, making it great
value for money too.
Researchers were
surprised when they found that this new form of CoQ10 was 40% more effective
than
conventional CoQ10 in
slowing aging markers.
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Melatonin and the pineal gland:
The answer to programmed neuroendocrine and immune aging, to its prevention
and its reversal. The anti-aging molecule Melatonin
In spite of the political denigratory campaign against the anti-aging
properties of melatonin, it is beyond any doubt that exogenouse
administration of melatonin to aging rodents
postpones their aging and/ or prolongs their life. Of course, melatonin
serves to indicate that the pineal gland is directly involved in the aging
process. The pineal grafting experiments also serve to indicate that the
pineal gland, via its links to the entire neuroendocrine system, controls the
"programme of aging" and that in-fact an aging pineal can
accelerate aging even in a normal young animal carrying his own young pineal.
Melatonin delays and reverses menopause in women
Night levels of melatonin in mammals and man decline progressively in the
course of aging. Previous studies with laboratory animals had shown that
evening administration of melatonin in senescent animals, as well as
transplantation of a young pineal into old animals produces a true reversal
of sexual decay. This has been shown by measuring (in that part of the brain that
controls sexual organs and functions- the hippocampus), receptors which
regulate the synthesis of LH and FSH (gonadotropins) in the hypophysis. This
remarkable evidence induced us to evaluate the effects of melatonin in women
from pre-menopausal and peri-menopausal age (from 42 to 52 years of age)
until menopause (from 52 to 62 years of age). The question was: is pineal melatonin,
whose blood levels decline in the course of aging in the sexual-reproductive
tract of women, responsible for, or directly connected with the onset of
menopause? Are we able to modify or eventually delay menopase by evening
administration of melatonin?
In the course of six months, evening administration of 3mg melatonin
produced a clear-cut decrement in blood of the pituitary hormone LH
(which increases progressively in the course of aging). This was most
noticeable in the younger women (43 to 49 years of age). Therefore, the
recovery of pituitary function to a more juvenile pattern of regulation is
more pronounced and rapid in younger women (Figure 4a and 4b). This equaled
to an arrest and even a reversal of brain aging and restoration of
reproductive functions in the women taking evening melatonin.
As a confirmation of a restoration of thyroid and sexual functions
consequent to the evening use of melatonin, seven women, at 2 and more years
after onset of menopause (complete interruption of the menstrual cycle), have
now reacquired a normal and physiological menstrual cyclicity.
Finally, 96% of women who had taken melatonin declared a total
disappearance of morning depression, which is typical in perimenopausal and
menopausel women.
Our results demonstrate that a clear-cut, cause-effect relationship exists
between the function of the pineal gland and night secretion of melatonin on
one side, and aging of sexual functions on the other side. The decline of
synthesis and release of pineal melatonin during aging, signals to us a
central hypotlamaic alteration of the control of the juvenile hormonal
cyclicity and the progressive quenching of fertility in women. Our results
show that nocturnal administration of melatonin produces a recovery of
thyroid function (synthesis of T3 and T4) and pituitary (hypophysis)
sensitivity to ovary regulation (decrease of LH and FSH) in the direction of
a remarkable recovery of more juvenile sexual-reproductive functions.
It inhibits aging. Why? Simply because it prevents aging of the remarkable
"switchyard" in the pineal gland (which truly is not a
typical gland!). Nocturnal administration of melatonin prevents the pineal from deteriorating,
from decaying into a heap of scrap, and thus from becoming unsuitable to
deliver the precise signals which regulate the natural rhythms of day and night.
These precise messages keep us constantly synchronized through the hormonal
system with the environment in which we live. If and when we stray from this
natural pathway, we develop diseases and age more rapidly.
But is melatonin a true hormone? No! Can it induce damage? No! Melatonin
is produced and secreted by different tissues and organs, but during
night-time only by the pineal gland. Even at huge dosages and for very long
periods, melatonin is totally harmless. Well documented data for this exists!
However, a few milligrams (3mg) of melatonin suffices to put the pineal at
"night rest" and thus to protect the pineal, our hormonal
switchboard center, from aging! If the pineal does not age, we cannot
possibly age, or at least the aging process will never again be as we have
seen and experienced it until now.
Melatonin is, a "gift of God" and can harm only those who
do not take it! People (especially women), are now able to appreciate what
hormonal and metabolic aging means and thus also prevent it. Others, let them
wait to have "youth genes" inserted! At present, 3 milligrams of
melatonin and zinc is sufficient for me and all those dear to me before
switching off the light and sinking into refreshing sleep
The basic experimental findings of 35 years of research, resulted in the
discovery of the undeniable existence of a programmed "Aging Clock"
in the pineal gland complex of the brain.
Melatonin must be taken late in the evening at bedtime in order to mimic
and restore the physiological night peak, which normally declines
progressively during the course of aging. As mentioned in the literature
reported above, the progressive abrogation of melatonin night-cyclicity
during aging is considered to be a basic signal expressing the extinction of
the most fundamental regulatory system in the body. This brain
"clock" is genetically and evolutionary linked to the sun, the
planetary system and the obvious dependence of our health from daily and
nocturnal, rhythmic cyclicity. Every person expresses their own genetically
inherited nocturnal peak of melatonin with very large individual variability.
However, in the majority of the population, the night elevation of melatonin
declines and most of us become "flat" after 80 years of age. This
is a basic aging message from the "clock"
Circadian, night melatonin seems to produce a resynchronization of the
entire neuroendocrine system and will certainly improve metabolic and
hormonal functions, including blood pressure, cholesterol levels, thyroid,
gonadal and adrenal functions. These effects can be easily evaluated with a
routine check-up. Melatonin will counteract the negative side-effects of
corticosteroids and of di-stressful agents, thus protecting the immune
system. Melatonin does not induce sleep but facilitates its onset and
produces a sleep pattern which is typical of children or young persons. It
greatly improves the quality of sleep and its restoring physical and
psychological effects, with a clear improvement of morning mood and body
muscle strength.
Melatonin is not a drug and it is not itself a cure for any disease!
Melatonin is ubiquitous in nature, cells, plants, animals, tissues and any
living organism. Milk, vegetables, cereals, rice, meat, etc., contain
variable amounts of melatonin.
Melatonin produced by the pineal gland seems to be responsible for the
night peak, while melatonin produced by the gut and the retina does not seem
to affect the nocturnal levels. It is thus evident that the night peak of melatonin initiates a sequence of positive effects
with a cascade of events which maintain the body systems synchronized with
the physiological cyclicity of hormones and cells. This night
"signal" is essential for the maintenance of immunity and the
"surveillance" against the onset of tumors. Therefore melatonin is
a fundamental element for prevention of aging-related diseases, including
cancer, autoimmune and cardiovascular diseases. Melatonin modulates and
controls the synthesis and secretion of all hormones within a circadian and
seasonal periodicity and variability. It has been given at a huge dosage of
grams daily for prolonged periods, and to 1500 women at the daily dosage of
300mg for years with no observed late side-effects and consequences. The
administration of melatonin to restore the physiological adaptation of the
body to circadian and seasonal periodicity is only the beginning of a new
medicine based on the concept that nobody can escape the established laws of
Nature within the solar-planetary system, in which man developed as a
mammalian species. We must be able to restore and correct the derangements of
this adaptation system and maintain it in its original juvenile conditions.
These metabolic conditions can be perfectly measured and maintained under
balance. Melatonin is perfectly suitable to re-synchronize all neuroendocrine
functions. It contains basic elements which will synergize in order to obtain
more rapid effects and to compensate the loss of fundamental minerals, due to
a wrong diet or to aging. The beneficial effects of melatonin in the
normalization of zinc levels have been scientifically proven and constitute a
basic tool for maintenance of hormonal and immune functions and to restore
these functions during aging.
This article is modified from the original version By Walter Pierpaoli
M.D., Ph.D.
HOW TO STOP AGING?
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